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Mathematical Models in Signaling Systems

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2004 Program and Audio Presentations

Keynote Address Session I Detailed Local Models of Signaling Pathways
Session II Cellular Models and Spatial Complexity Session III Experimental Approaches to Understanding Networks
Lunch Discussion Mathematical Challenges in System Biology Session IV Analysis of Network Architecture
Final Address and Dinner

Keynote Address

Leroy Hood, MD, PhD
Institute for System Biology

AbstractPDF icon   

Session I Detailed Local Models of Signaling Pathways

Andre Levchenko, PhD
John Hopkins University
NF-kb Isoforms and Switching Functions in Gene Regulation

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Presentation Audio icon

David de Graaf, PhD
AstraZeneca

AbstractPDF icon
Doug Lauffenburger, PhD
Massachusetts Institute of Technology (Abstract)
Multivariate Cue/Signaling/Response Analysis of Cell Decision Processes

Abstract PDF icon
Presentation Audio icon

James M. McCollum
Accelerating Exact Stochastic Simulation of Coupled Chemical Reactions

Presentation Audio icon


Session II Cellular Models and Spatial Complexity

Dennis Bray, PhD
University of Cambridge
Abstract PDF icon
Emmanuele DiBenedetto, PhD
Vanderbilt University
Mathematical Model of the Spatio-Temporal Dynamics of Second Messengers in Visual Transduction
Abstract PDF icon
Presentation Audio icon
Marc Kirschner, PhD
Harvard Medical School
Mathematical Modeling of Wnt Signaling

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Presentation Audio icon

Joseph Levine
Massachusetts Institute of Technology
Stochastic Analysis of a Phosphorylation Cycle
Presentation Audio icon

Session III Experimental Approaches to Understanding Networks

Naama Barkai, PhD
Weizmann Institute of Science
Abstract PDF icon

Stephen Michnick, PhD
University of Montreal
Towards a Molecular Spectrometer of the Cell

Abstract PDF icon
Presentation Audio icon

William Bialek, PhD
Princeton University
Noise and Information Flow in Biochemical Signaling

Abstract PDF icon
Presentation Audio icon

Chinlin Guo, MD, PhD
Harvard University
The Mechanism for Polarity Control and its Influence on Gradient Detection

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Michael J. Stern
Yale University School of Medicine
Dynamic Modeling of Developmental Genetics Using Computer Science Methodologies for System Design
Presentation Audio icon

Lunch Discussion Mathematical Challenges in System Biology

John Doyle, PhD
California Institute of Technology
Mathematical Challenges in Systems Biology
Presentation Audio icon

Session IV Analysis of Network Architecture

Rama Ranganathan, MD, PhD
The University of Texas Southwestern Medical Center at Dallas
Evolutionary Rules for Specific Protein Folding and Function
Abstract PDF icon
Ravi Iyengar, PhD
Mount Sinai School of Medicine
Analysis of Regulatory Loci within Signaling Networks
Abstract PDF icon
John Doyle, PhD
California Institute of Technology
Universal Organizing Principles of Networks

Abstract PDF icon
Presentation Audio icon

Keith O. Elliston, PhD
Genstruct, Incorporated

Abstract PDF icon


Final Address and Dinner

Marc Kirschner, PhD
Harvard Medical School